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In most research studies, the dose has been 900 mg to 1,500 mg per day, usually divided into two or three doses and taken for one to three months
The STEP and SELECT trials, which enrolled over 20,000 total participants and followed outcomes for up to four years, showed durable weight reduction, improved cardiovascular markers, and reduced major adverse cardiac events
Heart Fail Rev 30 , 9911004 (2025)
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